1.蛋白质组学和蛋白质翻译后修饰

2.生物分子的分离分析与生物标志物的发现与验证

3.重大疾病的无损伤分子诊断

1.Xiao H*,Zhang L,Zhou H,Lee JM,Garon EB,Wong DT*. Proteomic analysis of human saliva from lung cancer patients using two-dimensional difference gel electrophoresis and mass spectrometry.Mol Cell Proteomics2012, 11(2):M111.012112.

2.Xiao H*,Wong DT*. Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry.Anal Chim Acta2012, 723:61-67.

3.Xiao H*,Wong DT*.Method development for proteome stabilization in human saliva.Anal Chim Acta2012, 722:63-69.

4.Zhang L†,Xiao H*†,Zhou H,Santiago S,Lee JM,Garon EB,Yang J,Brinkmann O,Yan X,Akin D,Chia D,Elashoff D,Park NH,Wong DT*. Development of transcriptomic biomarker signature in human saliva to detect lung cancer.Cell Mol Life Sci.2012, 69(19):3341-3350.

5.Zhang L†,Xiao H†,Karlan S†,Zhou H†,Gross J,Elashoff D,Akin D,Yan X,Chia D,Karlan B,Wong DT.Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer.PLoS ONE2010, 5(12):e15573.
(†:Equal Contribution)