代表性论文(*:共同通讯作者,#:并列第一作者)
1.Kulaberoglu Y
#, Lin K
#, Holder M, Gai Z, Gomez M, Shifa BA, Mavis M, Hua L, Sharif AAD, Lujan C, Smith EJ, Bjedov I, Tapon N,
Wu G*, Hergovich A*. Stable MOB1 interaction with Warts/LATS, not Hippo/MST, is essential for development and tissue growth control in Hippo signaling.
Nat CommunAccepted. (2017)
2.Qian T, Wo J, Zhang Y, Song Q, Feng G, Luo R, Lin S*,
Wu G*, Chen HF*. Crystal structure of StnA for the biosynthesis of antitumor drug streptonigrin reveals a unique substrate binding mode.
Sci Rep7:40254. (2017)
3.Gai Z, Wang Q, Yang C, Wang L, Deng W,
Wu G*. Structural mechanism for the arginine sensing and regulation of CASTOR1 in the mTORC1 signaling pathway.
Cell Discov2:16051. (2016)
4.Gai Z, Chu W, Deng W, Li W, Li H, He A, Nellist M,
Wu G*. Structure of the TBC1D7-TSC1 complex reveals that TBC1D7 stabilizes dimerization of the TSC1 C-terminal coiled coil region.
J Mol Cell Biol8:411-425. (2016)
5.Zhao G, Chen C, Xiong W, Gao T, Deng Z,
Wu G*, He X*. Structural basis of the substrate preference towards CMP for a thymidylate synthase MilA involved in mildiomycin biosynthesis.
Sci Rep6:39675. (2016)
6.Zhang Z, Akyildiz S, Xiao Y, Gai Z, An Y, Behrens J*,
Wu G*. Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners.
Cell Discov1:15016. (2015)
7.
Wu G
#, Chen D
#, Tang H
#, Ren Y, Chen Q, Lv Y, Zhang Z, Zhao YL*, Yao Y, Xu P*. Structural insights into the specific recognition of N-heterocycle biodenitrogenation-derived substrates by microbial amide hydrolases.
Mol Microbiol91:1009-1021. (2014)
8.Zhao G
#,
Wu G
#, Zhang Y, Liu G, Han T, Deng Z, He X*. Structure of the N-glycosidase MilB in complex with hydroxymethyl CMP reveals its Arg23 specifically recognizes the substrate and controls its entry.
Nucleic Acids Res42:8115-24. (2014)
9.Zhang Y, Fu L, Qi X, Zhang Z, Xia Y, Jia J, Jiang J, Zhao Y*, Wu G*. Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun4:2608. (2013)
10.Chen D, Tang H, Lv Y, Zhang Z, Shen K, Lin K, Zhao YL,
Wu G*, Xu P*. Structural and computational studies of the maleate isomerase Iso from
Pseudomonas putidaS16 reveal a breathing motion wrapping the substrate inside.
Mol Microbiol87:1237-1244. (2013)
11.Zhang Z, Chen L, Gao L, Lin K*, Zhu L, Lu Y, Shi X, Gao Y, Zhou J, Xu P, Zhang J*,
Wu G*. Structural basis for the recognition of Asef by Adenomatous Polyposis Coli.
Cell Res22:372-386. (2012) 被英国皇家学会院士Marian Bienz选入Faculty of 1000数据库
其他SCI论文:
12.Jiang H, Deng R, Yuang X, Shang J, Lu S, Zhao Y, Song K, Liu X, Zhang Q, Chen Y, Chinn YE,
Wu G, Li J, Chen G, Yu J*, Zhang J*. Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat Chem BiolAccepted. (2017)
13.Zhang K,
Wu G, Tang H*, Hu C, Shi T, Xu P*. Structural basis for the transcriptional repressor NicR2 in nicotine degradation from
Pseudomonas.
Mol Microbiol103:165-180. (2017)
14.21. Liu G, Zhang Z, Zhao G, Deng Z,
Wu G*, He X*. Crystallization and preliminary X-ray analysis of the type IV restriction endonuclease ScoMcrA from
Streptomyces coelicolor, which cleaves both Dcm-methylated DNA and phosphorothioated DNA.
Acta Crystallogr F71:57-60. (2015)
15.Jiang Y, Tang H*,
Wu G, Xu P*. Functional identification of a novel gene, moaE, for 3-succinoylpyridine degradation in
Pseudomonas putidaS16.
Sci Rep5:13464. (2015)
16.Zhang Y, An J, Yang G, Bai A, Zheng B, Lou Z,
Wu G, Ye W, Chen HF, Feng Y*, Manco G*. Active site loop conformation regulates promiscuous activity in a lactonase from
Geobacillus kaustophilusHTA426.
PLoS One10:e0115130. (2015)
17.Wang H, Zhang Y, Zhang Z, Jin WL*,
Wu G*. Purification, crystallization and preliminary X-ray analysis of the inverse F-BAR domain of the human srGAP2 protein.
Acta Crystallogr F70:123-126. (2014)
18.Xie Y, An J, Yang G,
Wu G, Zhang Y, Cui L, Feng Y*. Enhanced enzyme kinetic stability by increasing rigidity within the active site.
J Biol Chem289:7994-8006. (2014)
19.Li A, Zhang Y*, Wang C,
Wu G*, Wang Z. Purification, molecular cloning, and antimicrobial activity of peptides from the skin secretion of the black-spotted frog,
Rana nigromaculata.
World J Microbiol Biotechnol29:1941-1949 (2013)
20.Chen F, Zhang Z, Lin K*, Qian T, Zhang Y, You D, He X, Wang Z, Liang J, Deng Z,
Wu G*. Crystal structure of the cysteine desulfurase DndA of
Streptomyces lividanswhich is involved in DNA phosphorothioation.
PLoS One7:e36635. (2012)
21.Hu W, Wang C, Liang J, Zhang T, Hu Z, Wang Z, Lan W, Li F, Wu H, Ding J,
Wu G, Deng Z, Cao C*. Structural insights into DndE from
Escherichia coliB7A involved in DNA phosphorothioation modification.
Cell Res22:1203-1206. (2012)
22.Tang H, Yao Y, Wang L, Yu H, Ren Y,
Wu G, Xu P*. Genomic analysis of
Pseudomonas putida: genes in a genome island are crucial for nicotine degradation.
Sci Rep2:377. (2012)
23.Li Q, Feng J, Gao C, Li F, Yu C, Meng L, Zhang Z, Ma C*, Gu L*,
Wu G, Xu P. Purification and characterization of a flavin reductase from the biodesulfurizing bacterium
Mycobacterium goodiiX7B.
Process Biochem47:1144-1149. (2012)