2003 德国海德堡大学生物化学中心,分子细胞生物学专业,博士学位
2003-2004 耶鲁大学医学院细胞生物学系,博士后
2004-2011 哈佛大学医学院附属麻省总院神经病学系,博士后、讲师
2011- 哈佛大学医学院附属麻省总院神经病学系,助理教授
2014- 欧宝app官方网站下载药学院,药理学,特别研究员
2003 Ph.D., Heidelberg University Biochemistry Center
2003-2004 Postdoc, Department of Cell Biology, Yale University School of Medicine
2004-2011 Postdoc & Instructor, Department of Neurology, Massachusetts General Hospital & Harvard Medical School
2011-Present Assistant Professor of Neurology, Massachusetts General Hospital & Harvard Medical School
2014-Present Principal Investigator, School of Pharmacy, SJTU
1. McCory H, Williams D, Sapp E, Gatune LW, Wang P, DiFiglia M, Li X*. Glucose transporter 3 is a rab11-dependent trafficking cargo and its transport to the cell surface is reduced in neurons of CAG140 Huntington’s disease mice. Acta Neuropathol Commun, 2014, 2:178.
2. Li X*, Valencia A#, Sapp E, Masso N, Alexander J, Patrick R, Kegel KB, Aronin N, DiFiglia M. Aberrant Rab11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington’s disease. J Neurosci, 2010, 30: 4552-4561.
3. Li X*, Sapp E, Chase K, Comer-Tierney LA, Masso N, Alexander J, Patrick R, Kegel KB, Valencia A, Esteves M, Aronin N, DiFiglia M. Disruption of Rab11 activity in a knock-in mouse model of Huntington’s disease. Neurobiol Dis, 2009, 36: 374-383.
4. Li X, Standley C, Sapp E, Valencia A, Qin ZH, Kegel KB, Yoder J, Comer-Tierney LA, Esteves M, Chase K, Alexander J, Masso N, Sobin L, Zeitlin S, Bellve K, Tuft R, Lifshitz L, Fogarty K, Aronin N, DiFiglia M. Mutant huntingtin impairs vesicle formation from recycling endosomes by interfering with rab11 activity. Mol Cell Biol, 2009, 29: 6106-6116.
5. Li X, Kaloyanova D, van Eijk M, Eerland R, van der Goot G, Oorschot V, Klumperman J, Lottspeich F, Starkuviene V, Wieland FT & Helms JB. Involvement of a GPI-anchored protein in maintenance of the Golgi structure. Mol Biol Cell, 2007, 18:1261-1271.