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  林俐

  长聘教轨助理教授，博士生导师，上海市教委“晨光计划”学者。于2013年和2018年在欧宝app官方网站下载生物医学工程学院获得学士和博士学位；之后分别在上海交大和伊利诺伊大学香槟分校（UIUC，师从Shuming Nie教授）开展博士后研究。曾获SERS国际会议最佳墙报奖、IMCO2019国际会议最佳论文奖（Best paper award）等。在Nano Letters, ACS Nano, Nature Commuminations，Small Methods等期刊上发表高水平论文，被引600余次，担任多个SCI期刊的审稿人，现承担或参与多项国家自然基金项目、省部级和校级项目以及横向课题的研究。博士期间作为早期主要研发人开发新型拉曼光谱纳米探针GERTs，并作为技术顾问帮助实现大规模生产，有望作为首个拉曼显影示踪剂进入临床转化阶段。

  
  

  近年来的研究兴趣集中于基于光学方法的无创病灶定位和检测，包括近红外二区拉曼响应纳米探针的设计开发、深穿透拉曼光谱技术、拉曼图像重建和术中活体定位病灶。

  
  

  欢迎生医工、光学、化学、材料和光谱学领域的硕士、博士以及博士后加入课题组！同时，欢迎对科研感兴趣的本科生提前加入实验室。近年来已多次指导本科生毕业设计、大创、PRP等项目，并指导学生参与“挑战杯”科创竞赛获省部级奖励。可通过Email 直接与我联系。

基于深穿透光谱技术的小动物活体无创光学成像

基于拉曼光谱的胃癌的快速诊断及预后分析

近红外二区表面增强拉曼光谱探针的设计和开发

1. 国家自然科学基金青年项目，课题负责人，2019-2022

“近红外二区增强拉曼探针及其组织穿透深度研究”

2.欧宝app官方网站下载医工交叉研究基金青年项目，合作方负责人，2022-2024

“基于机器学习算法和光纤拉曼光谱系统的胃癌快速诊断研究”

3.上海市科委“科技创新行动计划”高新技术领域项目，子课题负责人，2021-2023

4. 上海市教委“晨光计划”，课题负责人，2022-2023

Featued Articles After 2021

1. Zongyu Wu, Binge Deng, Yutong Zhou, Haoqiang Xie, Yumin Zhang,Li Lin*, Jian Ye*. Non-invasive detection, precise localization, and perioperative navigation of in vivo deep lesions using transmission Raman spectroscopy.Advanced Science.In press. (IF=17.2)

2. Yumin Zhang,Li Lin*, Jian Ye*. A rapid and universal method for depth estimation of lesions in heterogeneous tissues via photosafe ratiometric transmission Raman spectroscopy.View, 2023, 20230022.

3. Yumin Zhang, Ruoyu Chen, Fugang Liu, Peng Miao,Li Lin*, and Jian Ye*. In Vivo Surface-Enhanced Transmission Raman Spectroscopy under Maximum Permissible Exposure: Toward Photosafe Detection of Deep-Seated Tumors.Small Methods,2023, 7(2), 2201334. (IF=15.2)

4.Li Lin, Ruiyang Xue, Shuming Nie. "Surface-enhanced Raman scattering (SERS) nanoparticles for biodiagnostics, bioimaging, and spectroscopy-guided cancer surgery", In: Reference Module in Materials Science and Materials Engineering, Elsevier, 2022. (Invited Book Chapter)

5. Haoqi He, Yumin Zhang, Shuo Zhu, Jian Ye*, andLi Lin*. "Resonant strategy in designing NIR-II SERS nanotags: a quantitative study."The Journal of Physical Chemistry C, 2022, 126, 12575. (IF=4.2)

6. Yao Lu,Li Lin*, Jian Ye*, “Human metabolite detection by surface-enhanced Raman spectroscopy”,Materials Today Bio, 2022, 13, 100205. (IF=10.5)

7.Li Lin, Jian Ye, “Spontaneous Raman and Surface-Enhanced Raman Scattering Bioimaging.” In: Wei X., Gu B. (eds) Optical imaging in Human Disease and Biological Research. Advances in Experimental Medicine and Biology, vol 3233. Springer, Singapore, 2021, pp177-195. (Invited Book Chapter)

Featured Articles Before 2021

1. Yuqing Gu, Chang He, Yuqing Zhang,Li Lin, Benjamin David Thackray, Jian Ye*, “Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels”,Nature Communications, 2020, 11, 516. (IF=13.8)

2.Li Lin, Qiang Zhang, Xiyao Li, Meng Qiu, Xin Jiang, Hongchen Gu*, Dang Yuan Lei*, Jian Ye*, “Electron Transfer in Plasmonic Nanogaps Interrogated with Surface-Enhanced Raman Scattering,”ACS Nano, 2018, 12, 6492. (IF=15.8)

3.Li Lin, Zhonghui Liu, Xiyao Li, Hongchen Gu, Jian Ye*, “Quantifying the Reflective Index of Nanometer-Thick Molecular Layers on Nanoparticle,”Nanoscale, 2017, 9, 2213. (IF=7.2)

4.Li Lin, Mario Zapata, Min Xiong, Zhonghui Liu, Shanshan Wang, Hong Xu, Andrei G. Borisov, Hongchen Gu, Peter Nordlander*, Javier Aizpurua*, Jian Ye*, “Nanooptics of Plasmonic Nanomatryoshkas: Shrinking the Size of a Core–Shell junction to Subnanometer,”Nano Letters,2015, 15, 6419. (IF=11.1)